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J Clin Pharm Ther 2001;26:271-8. 2020;2020:8401239. Part 182 -- Substances Generally Recognized As Safe. In general, the safety and effectiveness of alternative medicines have not been scientifically proven and remain largely unknown. Lapi F, Gallo E, Bernasconi S, et al. Liang, R., Chen, M. R., and Xu, X. Koster, M. and David, G. K. Reversible severe hypertension due to licorice ingestion. View abstract. Eur J Clin Pharmacol 2010;66(8):805-810. Eagon PK, Elm MS, Hunter DS, et al. J Tradit.Chin Med 2010;30(1):47-50. Zhong Xi Yi Jie He Za Zhi 1990;10:101-2, 70. . View abstract. "It contains liquiritin, an active compound that helps to disperse and remove existing melanin in the skin," explains Chwalek. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. View abstract. This could change the effects and side effects of these medications. 2005;25(6):540-542. Phytother.Res 2004;18(3):241-243. J Clin Psychopharmacol 2008;28(3):264-370. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Oh, G. S., Pae, H. O., Choi, B. M., Lee, H. S., Kim, I. K., Yun, Y. G., Kim, J. D., and Chung, H. T. Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. J Pharmacol Exp Ther 2006;316:1369-77. typica. Licorice or Mulethi, also known as "Sweetwood", is an effective and potent medicinal herb. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . View abstract. View abstract. What are the side-effects of taking liquorice? Chen, M. F., Shimada, F., Kato, H., Yano, S., and Kanaoka, M. Effect of oral administration of glycyrrhizin on the pharmacokinetics of prednisolone. Blood Press 2009;18:192-5. Biofactors 2009;35(1):98-104. Melzer J, Rosch W, Reichling J, et al. An open study of 100 women with uterine fibroids showed that peony reduced the size of . View abstract. View abstract. View abstract. 2003;84(1):85-89. This formula has also been shown to dramatically relieve various types of spasmodic pain such as muscle cramps in the back and legs (restless legs) stiff muscles premenstrual cramping sciatica and abdominal pain. View abstract. View abstract. Wu, T. H., Chiu, T. Y., Tsai, J. S., Chen, C. Y., Chen, L. C., and Yang, L. L. Effectiveness of Taiwanese traditional herbal diet for pain management in terminal cancer patients. View abstract. Gibertoni, M., Bonito, V., Colombo, A., Falasca, A., and Nichelli, P. [Licorice-induced myopathy. Doeker, B. M. and Andler, W. Liquorice, growth retardation and Addison's disease. Plant Description. Saeedi, M., Morteza-Semnani, K., and Ghoreishi, M. R. The treatment of atopic dermatitis with licorice gel. Eur.Arch.Paediatr.Dent 2010;11(6):274-278. The chemicals in licorice are thought to . View abstract. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Liquorice supplements de Klerk GJ, Nieuwenhuis G, Beutler JJ. Yang DG. Side-effects of low-potassium levels can include lethargy and abnormal heart rhythms. View abstract. View abstract. Zhang W, Leonard T, Bath-Hextall F, et al. Lee, C. H., Park, S. W., Kim, Y. S., Kang, S. S., Kim, J. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. View abstract. View abstract. Licorice root is aromatic and is used as a flavoring agent in tea and other beverages. Volatiles with antimicrobial activity from the roots of Greek Paeonia taxa. Taking peony root along with phenytoin might decrease the effects of phenytoin and increase the risk of seizures. View abstract. This versatile anti-inflammatory plant can benefit digestive issues, hormone health, and skin health as well as helping ease problems with menstruation and menopause. Lipids Health Dis 2011;10:29. Am J Respir.Cell Mol.Biol. Am.J Chin Med 2004;32(4):569-578. View abstract. View abstract. View abstract. Int J Environ Res Public Health 2021;19(1):242. J Telemed Telecare. Amato P, Christophe S, Mellon PL. Z Gastroenterol 2001;39(7):511-7. Double-blind, placebo-controlled, randomized, pilot clinical trial of ImmunoGuard--a standardized fixed combination of Andrographis paniculata Nees, with Eleutherococcus senticosus Maxim, Schizandra chinensis Bail. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection. View abstract. A Rutgers expert discusses how eating black licorice can affect your health. This week, The New England Journal of Medicine reported that a man with a poor diet died of cardiac arrest after eating a bag-and-a-half of black licorice daily for weeks. Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. Wang H, Dong L, Qu F, et al. Hossain, M. S., Takimoto, H., Hamano, S., Yoshida, H., Ninomiya, T., Minamishima, Y., Kimura, G., and Nomoto, K. Protective effects of hochu-ekki-to, a Chinese traditional herbal medicine against murine cytomegalovirus infection. Read more. Hyodo T, Taira T, Kumakura M, et al. Exploring Pseudohyperaldosteronism in Glycyrrhizic Acid Toxicity From Chronic Licorice Root Consumption. Robles BJ, Sandoval AR, Dardon JD, Blas CA. J Clin Periodontol 1991;18(3):210-212. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. 2017 Sep;31(9):1330-1340. Nephol Dial Transplant 1999;14:218-20. J Altern Complement Med. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. Imtiaz, K. E. Sweet root, bitter pill: liquorice-induced hyperaldosteronism. 2020 Dec;58(1):352-356. We currently have no information for PEONY overview. Attou R, Redant S, Honore PM, Preseau T, Hantson P, De Bels D. Liquorice intoxication can lead to cardiac arrest! . Zhou, Y., Huang, Z., and Huang, T. [Clinical study of shengxue mixture in treating aplastic anemia]. J Clin Psychopharmacol 2016;36(6):572-9. Licorice-induced hypermineralocorticoidism. Biol Pharm Bull. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(12):1121-1123. Anon. Isr J Dent Sci 1989;2(3):153-157. Life Sci 9-27-2002;71(19):2267-2277. Phytother Res 2008;22(6):709-724. View abstract. Digestion 2004;69:45-52. Engqvist, A., von Feilitzen, F., Pyk, E., and Reichard, H. Double-blind trial of deglycyrrhizinated liquorice in gastric ulcer. Int Immunopharmacol 2012;14(1):27-31. This might increase the effects and side effects of methotrexate. Kase Y, Saitoh K, Ishige A, et al. Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. Dellow EL, Unwin RJ, Honour JW. [RETRACTED]. The anti-estrogenic action of beta-glycyrrhetinic acid. May Harm Baby During Pregnancy. Anesth Analg 2009;109(1):77-81. Madisch A, Holtmann G, Mayr G, et al. View abstract. View abstract. Red Peony Root (Paeniae Rubra Radix) 8 g Myrrh (Myrrha) . However, taking too much licorice root may cause side effects. Tacconi, P., Paribello, A., Cannas, A., and Marrosu, M. G. Carpal tunnel syndrome triggered by excessive licorice consumption. Bell ZW, Canale RE, Bloomer RJ. J Ethnopharmacol 2011;135(1):162-72. Brit Med J 1952;1:360-361. Life Sci 2-23-2001;68(14):1687-1694. Ir J Med Sci 2016;185(4):945-7. . Dobbins, K. R. and Saul, R. F. Transient visual loss after licorice ingestion. View abstract. MacKenzie, M. A., Hoefnagels, W. H., Jansen, R. W., Benraad, T. J., and Kloppenborg, P. W. The influence of glycyrrhetinic acid on plasma cortisol and cortisone in healthy young volunteers. View abstract. Peters, M. C., Tallman, J. Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. Korri, H., Awada, A., Baajour, W., Beaini, M., and Nasreddine, W. [Rapidly progressing quadriparesis secondary to licorice (souss) intoxication]. Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin. [Severe hypokalemia after holidays return]. Foster CA, Church KS, Poddar M, Van Uum SH, Spaic T. Licorice-induced hypertension: a case of pseudohyperaldosteronism due to jelly bean ingestion. Hypokalemic paralysis due to licorice consumption is extremely rare, with only 40 cases in the English literature describing paralysis secondary to exposure to licorice in candies, medications, chewing tobacco, and herbal preparations. View abstract. Phytother Res 2006;20(8):687-695. Sato H, Goto W, Yamamura J, et al. Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information. Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora. Read about Peony uses, side effects, health benefits, interactions, dose, warnings, and precautions. Prudden JF. When eaten in large quantities, black licorice can cause serious health issues. Fan ZJ, Liu JM, Li XX, et al. It's not suggested to take St. John's wort if you take blood thinners. Lorenzin, F., Degen, C., Milani, A., Siciliano, M., and Rossi, L. [Pseudo-hyperaldosteronism caused by licorice. View abstract. Myopathies associated with red yeast rice and liquorice: spontaneous reports from the Italian Surveillance System of Natural Health Products. View abstract. View abstract. Cureus 2020;12(11):e11656. I. Elucidation of five new flavonoid constituents from the roots of Glycyrrhiza glabra L. collected in Xinjiang. The roots are commonly used in Traditional Chinese Medicine (TCM) for many purposes. Fung AY, Look PC, Chong LY, et al. View abstract. View abstract. But I didn't take it long enough to see any change. 1991;78(1-2):1-6. Au, T. K., Lam, T. L., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of HIV-1 integrase inhibition by aqueous and methanol extracts of Chinese medicinal herbs. J Clin Hypertens (Greenwich) 2008;10:153-7. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. View abstract. J Med Liban 2012;60(2):117-119. Huang, W. W., Wang, M. Y., Shi, H. M., Peng, Y., Peng, C. S., Zhang, M., Li, Y., Lu, J., and Li, X. Feng ZT, Xu J, He GC, Cai SJ, Li J, Mei ZG. Best Underarm Whitening Creams For You 1. View abstract. That's because licorice real black licorice, not the phony licorice-flavored stuff flavored with anise oil . An evaluation of the efficacy of licorice gargle for attenuating postoperative sore throat: a prospective, randomized, single-blind study. Fortschr.Med 7-30-1992;110(21):395-398. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., and Bielenberg, J. Antiviral effects of Glycyrrhiza species. The benefits of licorice root can be enjoyed as a tea, supplement, tincture, or topical treatment, and even as candies. View abstract. Yasue H, Itoh T, Mizuno Y, Harada E. Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. Taking licorice and loop diuretics together might make potassium levels drop too low. Int Hepatol Comm 1997;233-238. [Effect of fu-zheng qu-xie on gastric disease infected with Campylobacter pyloridis]. A., Ziaee, A., and Samimi, R. The efficacy of licorice root extract in decreasing transaminase activities in non-alcoholic fatty liver disease: a randomized controlled clinical trial. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Glycyrrhizin-induced reduction of ALT in European patients with chronic hepatitis C. Am J Gastroenterol 2001;96(8):2432-2437. View abstract. Yoon JY, Cha JM, Hong SS, et al. It combined licorice, dates, peonies, and skullcap, and was traditionally prepared as a tea. A newly-filed federal lawsuit claims eating too much of The Hershey Company's Good & Plenty and black licorice Twizzlers candies can cause serious health problems, maybe even death. Prieto JM, Recio MC, Giner RM, et al. View abstract. Apparantly it's the one most important thing that shouldn't mix with Prednisolone and it makes withdrawal symptoms much worse. In a 30-day study in 50 adults with indigestion, taking a 75-mg licorice . Information from this source is evidence-based and objective, and without commercial influence. View abstract. Schleimer, R. P. Potential regulation of inflammation in the lung by local metabolism of hydrocortisone. NOW Supplements, Licorice Root (Glycyrrhiza glabra) 450 mg, Herbal Supplement, 100 Veg Capsules 208. Peony might slow blood clotting. J Altern Complement Med 2000;6:557-9. Bernardi, M., D'Intino, P. E., Trevisani, F., Cantelli-Forti, G., Raggi, M. A., Turchetto, E., and Gasbarrini, G. Effects of prolonged ingestion of graded doses of licorice by healthy volunteers. Davis EA, Morris DJ. They also have a range of other intriguing activities. View abstract. Eur J Pharmacol 1981;72:219-25.. View abstract. 2014 Jan;35(1):87-99. 1999;15:499-523. Phytother.Res. View abstract. Mattarello MJ, Karbowiak I, Ermolao A, and et al. I like herbal and fuit teas and a particular favourite of mine contains liquorice. Peony and its major constituent, paeoniflorin, improve radial maze performance impaired by scopolamine in rats. But the potential side effects are real enough. Peony root might decrease the amount of phenytoin in the body. View abstract. Hsiang, C. Y., Hsieh, C. L., Wu, S. L., Lai, I. L., and Ho, T. Y. Inhibitory effect of anti-pyretic and anti-inflammatory herbs on herpes simplex virus replication. Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. Edelman ER, Butala NM, Avery LL, Lundquist AL, Dighe AS. Anti Erection Pill. In Vivo 2021;35(4):2163-2169. View abstract. Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? Medicine (Baltimore) 2018;97(11):e0073. Ou TT, Wu CH, Hsu JD, et al. View abstract. A. and Cunliffe, W. J. Self-medication with liquorice in a patient with Addison's disease. 2001;21(7):501-503. Lin, J. C. Mechanism of action of glycyrrhizic acid in inhibition of Epstein-Barr virus replication in vitro. Peony might change how quickly the liver breaks down these medications. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. In some cases, this might change the effects and side effects of a medication. Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. View abstract. View abstract. CJEM 2010;12(3):224-225. View abstract. Drug Metab Dispos 2002;30:709-15.. View abstract. Postgrad Med 2017;129(3):329-31. Deglycyrrhizinated liquorice in aphthous ulcers. Effect of preoperative licorice lozenges on incidence of postextubation cough and sore throat in smokers undergoing general anesthesia and endotracheal intubation. Phytother Res 1988;2(3):140-145. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. 2020;383(13):1263-1275. mentioned adverse effects and recurrence rates. Some medications are changed and broken down by the liver. A 2020 review found that licorice root extract can help reduce the growth of . Lee, S., Lim, J. M., Jin, M. H., Park, H. K., Lee, E. J., Kang, S., Kim, Y. S., and Cho, W. G. Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin. Clin Neurol Neurosurg 2003;105:286-7.. View abstract. Gen Dent 2008;56(2):206-210. View abstract. Some research studies have found Angelica Sinensis to be beneficial for its effects on some symptoms of menopause. Chewing tobacco flavored with Licorice may cause serious side effects such as high blood pressure. Migraine is a type of headache. View abstract. Licorice might increase blood pressure. Altern Med Rev 1999;4(3):178-188. Visavadiya, N. P. and Narasimhacharya, A. V. Hypocholesterolaemic and antioxidant effects of Glycyrrhiza glabra (Linn) in rats. Planta Med 1983;48(5):38-42. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. BMJ 1997;314:731-2. Licorice is an herb that grows in parts of Europe and Asia. Taking peony along with birth control pills might increase the risk of side effects. Herb-Drug Interaction Potential of Licorice Extract and Paclitaxel: A Pharmacokinetic Study in Rats. It shows a wide range of biological and pharmacological activities, including anti-inflammatory and immune regulatory actions. Martin, M. D., Sherman, J., van der Ven, V., and Burgess, J. Clin Ter 1990;132(1):55-58. Zhang XH, Lowe D, Giles P, et al. View abstract. J Nutr Sci Vitaminol. [The nature of an anticoagulant isolated from peonies in the central zone of Russia]. Zhonghua Yi Xue Za Zhi 1983;63:477-81. Gut 1978;19(9):779-782. A dual investigation of the effect of dietary supplementation with licorice flavonoid oil on anthropometric and biochemical markers or health and adiposity. WebMD does not provide medical advice, diagnosis or treatment. 1. Liapina LA, Ammosova IaM, Novikov VS, et al. View abstract. Rackova, L., Jancinova, V., Petrikova, M., Drabikova, K., Nosal, R., Stefek, M., Kostalova, D., Pronayova, N., and Kovacova, M. Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin. Berlango Jimenez A., Jimenez Murillo L., Montero Perez F. J., Munoz Avila J. Paeoniae Radix-containing herbal medicine for patients with restless legs syndrome: A systematic review and meta-analysis. Sun, W. S., Imai, A., Tagami, K., Sugiyama, M., Furui, T., and Tamaya, T. In vitro stimulation of granulosa cells by a combination of different active ingredients of unkei-to. Acharya SK, Dasarathy S, Tandon A, et al. Black licorice contains a compound that comes from licorice root that can lower your potassium levels. View abstract. Liang Xiao, Wang YZ, Jing Liu, et al. Cooper, H., Bhattacharya, B., Verma, V., McCulloch, A. J., Smellie, W. S., and Heald, A. H. Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease. View abstract. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. 1987;(10):46-48. J Contemp Dent Pract 2010;11(1):E088-E094. Turpie AG, Runcie J, Thomson TJ. Kang, D. G., Moon, M. K., Choi, D. H., Lee, J. K., Kwon, T. O., and Lee, H. S. Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. Liquorice and hypertension. White Peony Tea Side Effects. View abstract. The efficacy of an ayurvedic preparation of yashtimadhu (Glycyrrhiza glabra) on radiation-induced mucositis in head-and-neck cancer patients: A pilot study. and its bioactive compounds. Ohta H, Ni JW, Matsumoto K, et al. Zhang W, Dai SM. Chien, C. F., Wu, Y. T., and Tsai, T. H. Biological analysis of herbal medicines used for the treatment of liver diseases. Other conditions. View abstract. [Clinical characteristics of five elderly patients with severe hypokalemia induced by glycyrrhizin derivatives]. Evid Based Complement Alternat Med. This Halloween, you'll want to stay vigilant about the candy . 2018 Jan;37(1):35-42. doi: 10.1007/s10067-017-3770-y. An Bras Dermatol 2010;85(5):613-620. van Marle J, Aarsen PN, Lind A, van Weeren-Kramer J. Deglycyrrhizinised liquorice (DGL) and the renewal of rat stomach epithelium. Hypertension encephalopathy after liquorice ingestion. J Hypertens 1985;3(1):19-23. View abstract. Zhong.Xi.Yi.Jie.He.Za Zhi. J Infect.Chemother. Complement Ther Clin Pract. The 1:1 of peony and licorice group can significantly reduced the ureteral smooth muscle tension and Christina Loosestrife herb can increase the u reteral tension, but the amount is too large, the mechanism may be related with the diuretic row stone. Objective: To evaluate the effect of different ratio of peony and licorice and Christina Loosestrife herb decoction on isolated in New Zealand . J Am Acad Dermatol 2011;65(4):699-714. Pharmazie 2010;65(8):624-8. Dying for a cup of tea. J Ethnopharmacol. Gardner Z, McGuffin M. Boca Raton, FL: CRC Press, 2013. The invention belongs to the field of biopesticides, and mainly discloses a nuisanceless biological compound pesticide and a preparation method thereof. Little is known about whether it's safe to use licorice root while breastfeeding. Chen MF, Shimada F, Kato H, Yano S, Kanaoka M. Effect of glycyrrhizin on the pharmacokinetics of prednisolone following low dosage of prednisolone hemisuccinate. Dai DW, Singh I, Hershman JM. Phytother Res. Kumada T, et al. Gut 1969;10:299-302. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. Ngan LT, Moon JK, Shibamoto T, Ahn YJ. Kitagawa, I., Chen, W. Z., Hori, K., Harada, E., Yasuda, N., Yoshikawa, M., and Ren, J. Evid Based Complement Alternat Med 2016;2016:9852793. Francini-Pesenti F, Puato M, Piccoli A, Brocadello F. Liquorice-induced hypokalaemia and water retention in the absence of hypertension. . Murck H, Lehr L, Hahn J, Braunisch MC, Jezova D, Zavorotnyy M. Adjunct Therapy With Glycyrrhiza Glabra Rapidly Improves Outcome in Depression-A Pilot Study to Support 11-Beta-Hydroxysteroid Dehydrogenase Type 2 Inhibition as a New Target. Ma, X. F. [Experimental and clinical studies on the treatment of pulmonary heart disease and pulmonary hypertension with Paeonia lactiflora]. Koo YK, Kim JM, Koo JY, et al. Zhong Xi Yi Jie He Za Zhi 1991;11:102-4, 69. Scand.J Gastroenterol. View abstract. Bruynzeel DP. Deglycyrrhizinated liquorice in duodenal ulcer. 1991;4(2):166-173. Effects of the licorice extract against tumor growth and cisplatin-induced toxicity in a mouse xenograft model of colon cancer. Effects of cerebral ischemia-reperfusion on pharmacokinetic fate of paeoniflorin after intravenous administration of Paeoniae Radix extract in rats. Effects of low-dose liquorice alone or in combination with hydrochlorothiazide on the plasma potassium in healthy volunteers. 4-14-2001;145(15):744-747. Brasseur, A. and Ducobu, J. Zhong.Xi.Yi.Jie.He.Za Zhi. Int Immunopharmacol. QJM 2011;104(12):1093-1095. Preterm birth and licorice consumption during pregnancy. The glycyrrhizin and glycyrrhetic acid constituents of licorice have significant anti-androgen effects, 32-34 which may be helpful in reducing androgenic symptoms in women with PCOS. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. A laboratory evaluation of the antibacterial and cytotoxic effect of Liquorice when used as root canal medicament. Lancet 1992;340:13-17. Kent UM, Aviram M, Rosenblat M, Hollenberg PF. A., van der Ven, P. F., Martin, M., Sherman, J., and Haley, J. Int Urol Nephrol. View abstract. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. J Assoc Physicians India 1978;26(9):811-814. Man SC, Li XB, Wang HH, et al. He X, Xing D, Ding Y, et al. Electronic Code of Federal Regulations. [Application of dannang recipe no. View abstract. A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. View abstract. View abstract. Mu Y, Zhang J, Zhang S, et al. We describe a patient who suffered life-threatening hypokalemic paralysis caused by consumption of licorice in the form of a tea sweetener superimposed on long . Alt Med Rev 2001;6:495-9. Treatment of duodenal ulcer with glycyrrhizinic-acid-reduced liquorice. Pak J Med Sci 2022;38(1):271-275. Luo, Y. G., Liu, Y. Q., and Hu, J. View abstract. View abstract. Liang, R. N., Liu, J., and Lu, J. Previous studies have estimated that a dose of 1 to 5 grams (g) of licorice root daily is safe for most adults. View abstract. The sweet stuff in your kids' trick-or-treat buckets may come with a bitter side effect. View abstract. Lancet 2-10-1973;1(7798):294-295. Phytomedicine 2003;10:271-85. Lancet 1990;335(8697):1060-3. View abstract. J Biol Response Mod 1985;4:551-84. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. Cotterill, J. Wu G, Wu N, Li T, et al. View abstract. White Peony is technically named Peonia lactiflora, and in Chinese, it is named Bai Shao. J Endocrinol Invest 1996;19:624-9. Am J Nephrol 2000;20:145-8. Asian Medical Journal 1984;26(7):423-438. Hussain RM. View abstract. Clinical and immunological consequences of total glucosides of paeony treatment in Sjgren's syndrome: A randomized controlled pilot trial. To learn more about how herbs are used to treat infertility, see this article. Fuhrman, B., Volkova, N., Kaplan, M., Presser, D., Attias, J., Hayek, T., and Aviram, M. Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressure. View abstract. J Clin Endocrinol Metab 2003;88:2384-92. Other side effects of licorice use include . Zhongguo Zhong.Yao Za Zhi 2009;34(21):2695-2700. View abstract. [Study on activating blood and eliminating stasis of total paeony glycoside(TPG)]. Du, J. H. and Dong, B. D. [Comparative study on clinical efficacy of using methotrexate singly or combined with total glucosides of Paeony in treating rheumatoid arthritis]. Kang, J. H., Park, Y. H., Choi, S. W., Yang, E. K., and Lee, W. J. Resveratrol derivatives potently induce apoptosis in human promyelocytic leukemia cells. View abstract. Guo TL, Zhou XW. View abstract. (Doses up to 60 grams daily for up to 4 months have been used without reported adverse effects.) View abstract. Licorice, tobacco chewing, and hypertension. 2019;35:329-41. Armanini D, Lewicka S, Pratesi C, et al. View abstract. 17. A., Keller, W. J., Pereira, M. A., and Kinghorn, A. D. Anti-oxidant constituents of the roots and stolons of licorice (Glycyrrhiza glabra). Peony might have some of the same effects as estrogen. Too much black licorice, the federal agency says, can lead to "abnormal heart rhythms, as well as high blood pressure, edema (swelling), lethargy, and congestive heart failure." . Immediately afterwards, Teacher Liu looked at her, picked up her paper, and said, Student Zhou Xiaotong, this time I ll give you a warning.