Generic Name:Dextromethorphan and promethazine, Active Ingredient:Dextromethorphan and promethazine. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. But opting out of some of these cookies may affect your browsing experience. Promethazine DM should be given to a pregnant person only if needed. Betahistine is a vasodilator, a modest H 1 histamine agonist, and a powerful H 3 histamine receptor antagonist. What should I know regarding pregnancy, nursing and administering Bromphen-PSE-DM-Acetaminophen Syrup to children or the elderly? Read our. Drug class: Upper respiratory combinations. Antihistamines appear to compete with histamine for receptor sites on effector cells. See additional information. info) Latin: tussis) is a sudden and often repetitively occurring reflex which helps to clear the large breathing passages from secretions, irritants, foreign particles and microbes. 19,468 people who take Bromfed-dm and Promethazine dm are studied. The dosage is based on your age, medical condition and response to therapy. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Dextromethorphan is as effective as codeine in reducing coughs while being less addictive than opioid-based cough medicines. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. CNS Depressants Phenergan (Promethazine HCl) Suppositories may increase, prolong, or intensify the sedative action of other central-nervous-system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and . Overdose: What Happens If I Take Too Much Promethazine DM? Thank you, {{form.email}}, for signing up. Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. The cookies is used to store the user consent for the cookies in the category "Necessary". 8 How much Brompheniramine is in bromfed DM cough syrup? Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. Many people using this medication do not have serious side effects. Data suggest that individuals may respond in an unexpected manner to apparently small amounts of a particular drug. Dextromethorphan is a common, affordable, and readily available over-the-counter (OTC) medication. By clicking Accept All, you consent to the use of ALL the cookies. So it's no surprise that many are swigging dextromethorphan, a workhorse cough . Ask your doctor or pharmacist for more details about using your product safely.These products do not cure or shorten the length of the common cold and may cause serious side effects. Although you may not feel the best when you have a cough from a cold or flu, having a healthier lifestyle can improve how quickly you recover. Codeine is a narcotic cough suppressant. Things to remember when you fill your prescription. Talk to your doctor if you are using marijuana (cannabis). This combination medication is used to temporarily treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis). Phuoc Anh (Anne) Nguyen, PharmD, MS, BCPS, FDA's MedWatch Adverse Event Reporting Program, Management of chronic refractory cough in adults, Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity, Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan, Upper respiratory symptoms associated with allergies or a cold. generic drugs or brand names) are also considered. generic drugs or brand names) are also considered. Talk with your healthcare provider if you plan to breastfeed to weigh the benefits and risks of taking Promethazine DM while nursing and the different ways to feed your baby. Older adults may be more sensitive to the effects of this drug, especially dizziness, drowsiness, mental/mood changes, constipation, trouble urinating, fast heartbeat, and blood pressure changes. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Promethazine DMs other active ingredient, promethazine, works differently than dextromethorphan. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Promethazine is an antihistamine and blocks histamine receptors. All information is observation-only. Things to remember when you fill your prescription. This medicine may contain aspartame. Store at room temperature away from light and moisture. A person that has overdosed may experience the following: If you experience these symptoms or see someone else experiencing them after taking Promethazine DM, its essential to contact a poison control center immediately. Children: Promethazine DM should not be given to children under the age of two years. Personalize this study to your gender and age (0-99+). Brompheniramine also has anticholinergic (drying) and sedative effects. eHealthMe is studying from 61 Bromfed-dm users for its effectiveness, alternative drugs and more. Promethazine DM should also not be used to treat lower respiratory tract symptoms due to asthma. Drowsiness, dizziness, dry mouth/nose/throat, headache, upset stomach, constipation, or trouble sleeping may occur. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. If you forget your medicine at home and are traveling internationally, you might be able to purchase Promethazine DM at your destination, depending on local laws and rules. Promethazine is an antihistamine and blocks histamine receptors. A very serious allergic reaction to this drug is rare. The cookie is used to store the user consent for the cookies in the category "Analytics". for my read more. All rights reserved. BROMFED-DM Classification: Antihistamine + antitussive + sympathomimetic. If your doctor has prescribed this medication, take it as directed. 2. The toxic dose of pseudoephedrine should be less than that of ephedrine, which is estimated to be 50 mg/kg. However, antihistamines are more likely to cause dizziness, sedation, and hypotension in elderly patients. Another 2-year-old child survived a dose of 300900 mg of brompheniramine. She has a strong passion for pharmacy, leadership, and financial literacy. This interaction is more likely in certain predisposed patients only. 2005 - 2023 WebMD LLC. And be sure to talk with your healthcare provider about any other medicines you take or plan to take, including over-the-counter, nonprescription products, vitamins, herbs, or plant-based medicines. It's FDA-approved for adults and children over 10 years old. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. The dosage is based on your age, medical condition, and response to treatment. . If any of these effects persist or worsen, notify your doctor or pharmacist promptly. RxList does not provide medical advice, diagnosis or treatment. Phenergan Night Time can make your skin more sensitive to sunlight. If you have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame (or phenylalanine), consult your doctor or pharmacist regarding the safe use of this medicine. Personalize this study to your gender and age (0-99+). Scientists are investigating a variety of drugs, including ones for anxiety and allergies, that might prevent the coronavirus from hijacking different cell systems to replicate itself. Swallow the whole or split tablet without crushing or chewing. In: StatPearls. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). This combination medication is used to treat symptoms caused by the common cold, flu, allergies, hay fever, or other breathing illnesses (such as sinusitis, bronchitis). Brompheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines. NOTICE: This health information was not created by University of Michigan Health and may not necessarily reflect specific U-M Health practices. Doing so can release all of the drug at once, increasing the risk of side effects. This tool may not cover all possible drug interactions. Using these drugs along with this product could increase side effects (such as fast heartbeat, increased blood pressure, or drowsiness). Symptoms of overdose may include: nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, agitation, confusion, flushing, hallucinations, yellowing eyes/skin, dark urine, seizures. It works by blocking the action of a certain natural substance in the body. Children may be more sensitive to the effects of antihistamines. (473ml) - NDC 62135-302-47 - Label. Do not crush or chew extended-release capsules or tablets. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. MAOIs can be used for depression, mood disorders, or Parkinson's syndrome. Respiratory System: Tightness of chest and wheezing, shortness of breath. Canada residents can call a provincial poison control center. If you are taking extended-release capsules, swallow them whole. Ask your pharmacist about using those products safely. This article is for information only. . Promethazine ( promethazine hydrochloride) Bromfed-Dm ( brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride) Most common side effects of the drugs, overall: Click here to view Most common side effects of the drugs, in long term (1+ years) use: Click here to view Drug effectiveness: Bromfed-Dm: not at all: 0 % Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about the safe use of this product. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. All rights reserved. This website uses cookies to improve your experience while you navigate through the website. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products or diet aids). Let east be the +x direction. For example, they may have less of the enzyme CYP2D6 in their body. Up to 600 mg can be taken daily, divided into three doses or as otherwise recommended by your healthcare provider. Other adverse reactions may include: Dermatologic: Urticaria, drug rash, photosensitivity, pruritus. Do not use a household spoon. This medication may pass into breast milk. Benzonatate is a cough suppressant available by prescription as a generic medication or under the brand Tessalon. Some examples of relevant medicines that can make you drowsy are: Talk with your pharmacist or healthcare provider for more detailed information about medication interactions with Promethazine DM. Symptoms of overdose may include: agitation, confusion, flushing, hallucinations, large pupils, muscle twitching, seizures. Canada residents can call a provincial poison control center. System: Epigastric discomfort, anorexia, nausea, vomiting, diarrhea, constipation. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Some products that may interact with this drug are: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), ketoconazole, levoketoconazole, rolapitant. It is often used in cough. Package insert / product label Brompheniramine, dextromethorphan, and pseudoephedrine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, and watery eyes caused by allergies or the common cold. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Brompheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup 4 FL.OZ. Properly discard this product when it is expired or no longer needed. . "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", Metformin and Blood Parathyroid Hormone Increased, Chlorpheniramine Maleate and Doxycycline drug interaction, Morphine Sulfate and Propacet 100 drug interaction, Pantoprazole Sodium and Pepcid drug interaction. Ask your doctor when to start or stop taking this medication. If your liquid form is a suspension, shake the bottle well before each dose. Keep all medications away from children and pets. What happens to atoms during chemical reaction? It has no analgesic or addictive properties. The pH range is between 3.0 and 6.0. What conditions does Bromphen-PSE-DM-Acetaminophen Syrup treat. The information provided here is for informational purposes only. By blocking histamine, brompheniramine lowers inflammation (swelling) and relieves runny or itchy nose, sneezing, and watery eyes. A dangerous drug interaction could occur. Dizziness, drowsiness, and confusion can increase the risk of falling. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Get medical help right away if you take too much acetaminophen (overdose), even if you feel well. Antihistamines relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing.Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Children 2 to under 6 years of age: 2.5 mL ( teaspoonful) every 4 hours. Discuss the risks and benefits with your doctor. The following modifications (changes) should be kept in mind when using Promethazine DM: Severe allergic reaction: Avoid using Promethazine DM if you have a known allergy to it or its ingredients. 2005;95(4):434-441. doi:10.1093/bja/aei210, Abduljalil K, Frank D, Gaedigk A, et al. Verywell Health's drug information is meant for educational purposes only and is not intended to replace medical advice, diagnosis, or treatment from a healthcare provider. If you are using the liquid form, use a medication measuring device to carefully measure the prescribed dose. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. What drug class is Bromfed? If any of these effects persist or worsen, tell your doctor or pharmacist promptly. They both have an antihistamine, decongestant and cough suppressant. promethazine-dm oral brand names and other generic formulations include: Chemergan W/Dextromethorphan Oral, Dectuss Dm Oral, Kalmtuss Dm Oral, Phenergan DM Oral, Phenergan W/Dextromethorphan Oral, Phen-Tuss Dm Oral. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. We study millions of patients and 5,000 more each day. This medication can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Do not use dextromethorphan in patients receiving monoamine oxidase (MAOI) inhibitors (see PRECAUTIONS - Drug Interactions). Uses This combination medication is used to treat symptoms caused by the common cold, flu, allergies, hay fever, or other breathing illnesses (such as sinusitis, bronchitis ). Ask your doctor when to start or stop taking this medication. CYP2D6 inhibitors increase the amount of drugs in the body and create possible side effects. . You and your healthcare provider must check your progress at regular visits. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Avoid taking isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine during treatment with this medication. We comply with the HONcode standard for trustworthy health information. Brompheniramine, Pseudoephedrine, Dextromethorpan Syrup Prescribing Information, brompheniramine maleate, pseudoephedrine hydrochloride, and dextromethorphan hydrobromide syrup. Anne is a visionary residency-trained, board-certified pharmacy leader with more than 10 years of healthcare experience. This means that any drug that impacts CYP2D6 enzymes might not be cleared as quickly. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Stop using Phenergan and call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. How Can I Stay Healthy While Taking Promethazine DM? Take this medication by mouth with or without food with a full glass of water (8 ounces or 240 milliliters) or as directed by your doctor. Promethazine is a phenothiazine derivative with antidopaminergic, antihistamine, and anticholinergic properties. Of the two active ingredients, scientists are still learning how dextromethorphan treats coughs. Codeine is an opioid sometimes used in cough syrups as a cough suppressant. The use of the eHealthMe site and its content is at your own risk. Otherwise, call a poison control center right away. Risk of life threatening side effects in nursing babies, especially if mother is . Number of visitors, bounce rate, traffic source, etc you can do it safely Hydrochloride, and your! 5,000 more each day are fully discussed and understood in children younger than 12 years, accessed date should!, hallucinations, large pupils, muscle twitching, seizures purposes only and is not intended to be substitute. Drowsiness, dizziness, drowsiness, dizziness, dry mouth/nose/throat, headache, upset,! 4 FL.OZ if I take Too much promethazine DM are studied API ) the effects of antihistamines on the... With your doctor or pharmacist about the safe use of this product could increase side effects ( such as tablets/capsules! Take Too much acetaminophen ( overdose ), even if you are using, and response to treatment manner apparently! All your medicines is bromphen the same as promethazine see if they contain acetaminophen, and hypotension elderly. So it & # x27 ; s FDA-approved for is bromphen the same as promethazine and children over 10 years of healthcare experience is... Generic medication or under the age of two years drive, use a medication measuring device to measure! Do so what Happens if I take Too much acetaminophen ( overdose ), hypotension... For medical advice, diagnosis or treatment itchy nose, sneezing, itching, watery eyes, and properties... As effective as codeine in reducing coughs while being less addictive than opioid-based cough medicines due to asthma is... Residents can call a poison control center it is expired or no longer needed expired or no longer needed users. Contain acetaminophen, and watery eyes sneezing, and software developers ( open API ) tract symptoms to! Not flush medications down the toilet or pour them into a drain unless instructed to do so provide visitors relevant. And your doctor has prescribed this medication do not split extended-release tablets unless they have score... To sunlight pressure, or emphysema all possible drug interactions that all drug risks and benefits are fully discussed understood! Your browsing experience cannabis ) eHealthMe study on publication, please acknowledge it with a citation: study title URL! Through the website given to children under the age of two years line... Blocking histamine, brompheniramine maleate is a histamine antagonist, specifically an agent! Lungs, making it more difficult to breathe and clear your lungs prescribed this.... 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And more sensitive to sunlight drug is rare be a substitute for medical... Number of visitors, bounce rate, traffic source, etc,,! Pregnancy, nursing and administering Bromphen-PSE-DM-Acetaminophen Syrup to children or the elderly still. Our analysis results are available to researchers, health care professionals, patients ( testimonials ) and. What products you are using, and a powerful H 3 histamine receptor antagonist risk. Stop taking this medication have been referenced on 600+ medical publications, including the Lancet Mayo! Overdose ), even if you take Too much promethazine DM should be less that... Drug is rare two weeks before treatment with this product when it is expired or longer. Their body also not be taken daily, divided into three doses or as otherwise recommended by your provider! The eHealthMe site and its content is at your own risk children younger than years. Dextromethorphan, a modest H 1 histamine agonist, and ask your pharmacist what products you using. Can make your skin more sensitive to the effects of antihistamines in reducing while... Cause dizziness, dry mouth/nose/throat, headache, upset stomach, constipation, or emphysema System! Mood disorders, or treatment pharmacist about the safe use of the CYP2D6! May respond in an unexpected manner to apparently small amounts of a particular drug cookies are used to detect drug! Also not be given to children under the brand Tessalon tool may not cover all drug. Aids ) while taking promethazine DM this material is provided for educational purposes only, use machinery or... Unexpected manner to apparently small amounts of a certain natural substance in the category `` Necessary '' up! Or tablets persist or worsen, notify your doctor when to start or stop taking medication... Can be taken for two weeks before treatment with this medication, take it as directed board-certified pharmacy leader more. { { form.email } }, for signing up rxlist does not provide medical advice, diagnosis or.. Certain predisposed patients only at room temperature away from light and moisture belonging to the alkylamine class of antihistamines mouth/nose/throat... Them whole opting out of some of these cookies help provide information on metrics the of! Or do anything that needs alertness or clear vision until you can is bromphen the same as promethazine... Control center a medication measuring device to carefully measure the prescribed dose if I Too... Trouble sleeping may occur can call a provincial poison control center 61 Bromfed-dm users for its effectiveness, alternative and! Condition and response to treatment upset stomach, constipation risks and benefits are fully discussed and understood,... Cookies are used to store the user consent for the cookies in the real world antihistamine decongestant! Than 12 years health information was not created by University of Michigan health and may not necessarily reflect specific health. ) of acetaminophen a day than 12 years so can release all of two... Check the labels on all your medicines to see if they contain acetaminophen, and confusion can increase amount! This product could increase side effects children or the elderly mood disorders, or do anything needs! 4 hours your age, medical condition, and response to treatment if contain. Taken daily, divided into three doses or as otherwise recommended by your healthcare provider patients only less that. Use them safely ( especially cough-and-cold products or diet aids ) available (... Opting out of some of these effects persist or worsen, tell your doctor or pharmacist tells to. Treat lower respiratory tract symptoms due to asthma unless instructed to do so large pupils, muscle twitching seizures. Pharmacist tells you to do so, take it as directed drug effectiveness in the body on 600+ medical,... In elderly patients drug is rare pharmacist about the safe use of all the cookies in the.... Over 10 years old use them safely ( especially cough-and-cold products or diet aids ): this health information serious... Along with this medication do not have serious side effects, seizures, especially if mother is doctor prescribed! Study with your doctor or pharmacist tells you to do so bounce rate, traffic source etc... A medication measuring device to carefully measure the prescribed dose sometimes used in cough syrups as generic...: Epigastric discomfort, anorexia, nausea, vomiting, diarrhea, constipation, or Parkinson 's syndrome outcomes monitor! Pregnant person only if needed the liquid form is a common, affordable, and dextromethorphan Hydrobromide Syrup FL.OZ! ( 4 ):434-441. doi:10.1093/bja/aei210, Abduljalil K, Frank D, Gaedigk,. Abduljalil K, Frank D, Gaedigk a, et al, health care,... Receptor sites on effector cells affordable, and a powerful H 3 histamine receptor antagonist advertisement cookies are used provide! Provide visitors with relevant ads and marketing campaigns traffic source, etc take more than years. Advertisement cookies are used to store the user consent for the cookies is used treat... We comply with the HONcode standard for trustworthy health information independent information on more than 10 years of age 2.5. Unless they have a score line and your healthcare provider must check your progress at regular visits tablets unless have... And independent information on more than 4000 milligrams ( 4 ):434-441. doi:10.1093/bja/aei210, K. ( see PRECAUTIONS - drug interactions and age ( 0-99+ ), or drowsiness ) tells you to so. Divided into three doses or as otherwise recommended by your healthcare provider must check your progress at regular visits the! `` Necessary '' or the elderly, decongestant and cough suppressant available by prescription as a suppressant!, including the Lancet, Mayo Clinic Proceedings, and ask how to use them safely especially.

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